Silvers L W, Royster T S, Mulcare R J
Ann Surg. 1980 Aug;192(2):232-6. doi: 10.1097/00000658-198008000-00018.
One hundred six patients who underwent a total of 141 operations, on 156 limbs for peripheral arterial emboli from 1964 to 1979 were studied. The average age of the patients was 68.5 years. The source of the emboli in 76.4% of the patients was arteriosclerotic heart disease and atrial fibrillation. The presenting clinical symptoms and signs were the most accurate determinate of limb salvage. Our overall limb salvage was 86.5% and in the survivor population 93.9%. The overall hospital mortality was 21.7%. There were much higher morbidity and mortality rates associated with each subsequent embolic event. Particular attention was paid to factors related to recurrent emboli. The use of antigoagulants in the post embolectomy period does not have a statistically significant effect of preventing recurrent emboli.
对1964年至1979年间因外周动脉栓塞接受了总共141次手术、累及156条肢体的106例患者进行了研究。患者的平均年龄为68.5岁。76.4%的患者栓子来源为动脉硬化性心脏病和心房颤动。出现的临床症状和体征是肢体挽救最准确的决定因素。我们的总体肢体挽救率为86.5%,存活人群中为93.9%。总体医院死亡率为21.7%。每次后续栓塞事件的发病率和死亡率都高得多。特别关注了与复发性栓子相关的因素。在取栓术后使用抗凝剂对预防复发性栓子没有统计学上的显著效果。