Ikumo H
J Nutr. 1980 Oct;110(10):2045-50. doi: 10.1093/jn/110.10.2045.
Dilauryl succinate (DLS) and unsaturated fatty acids (UFA) were compared for the effects of inducing vitamin E deficiency symptoms in chicks. Experimental diets containing DLS, UFA and DLS + UFA, respectively, were given to 1-day-old chicks for 28 days. The diet containing DLS but not UFA showed far less increase in peroxide value than those containing UFA or DLS + UFA when left in a battery brooder of 30 degrees. Vitamin E deficiency symptoms in chicks given DLS + UFA were more severe than those in chicks fed either DLS or UFA. No significant difference in vitamin E deficiency symptoms except incidence of encephalomalacia was observed between the chicks given DLS and UFA. Extracting UFA from the diet containing DLS + UFA resulted in the reduction of vitamin E deficiency induction to the same degree as the diet containing DLS. Synthetic antioxidants were effective in alleviating the vitamin E deficiency symptoms in the chicks fed UFA and DLS + UFA, while only slightly effective in those given DLS. It was found that the effects of DLS and UFA can be separated and combined technically and it was suggested that they have different mechanism in inducing vitamin E deficiency.
比较了二月桂基琥珀酸酯（DLS）和不饱和脂肪酸（UFA）对雏鸡诱发维生素E缺乏症状的影响。分别给1日龄雏鸡喂食含DLS、UFA和DLS+UFA的实验日粮，持续28天。当置于30摄氏度的层架式育雏器中时，含DLS但不含UFA的日粮的过氧化值增幅远低于含UFA或DLS+UFA的日粮。喂食DLS+UFA的雏鸡的维生素E缺乏症状比喂食DLS或UFA的雏鸡更严重。在喂食DLS和UFA的雏鸡之间，除脑软化发病率外，未观察到维生素E缺乏症状的显著差异。从含DLS+UFA的日粮中提取UFA导致维生素E缺乏诱导程度降低至与含DLS的日粮相同。合成抗氧化剂对缓解喂食UFA和DLS+UFA的雏鸡的维生素E缺乏症状有效，而对喂食DLS的雏鸡仅略有效果。发现DLS和UFA的作用在技术上可以分离和组合，并且表明它们在诱发维生素E缺乏方面具有不同的机制。
