Moritsch E, Jarisch R, Konrad K
Laryngol Rhinol Otol (Stuttg). 1978 Sep;57(9):792-6.
Kaposi's sarcoma involvement of the ENT region develops normally years after the onset in the skin. Reports on Kaposi's sarcoma in the ENT literature are therefore very rare. Until now by no kind of treatment including X-ray irradiation satisfactory results could be obtained. The recently introduced longterm-treatment with vinblastine sulfate is very effective reducing the size and extension of the tumorous infiltrations. In the ENT-region the plate, the pharynx, the larynx and the trachea are most frequently involved. We report on a patient with extensive pharyngeal and laryngeal involvement who had to be tracheotomized. While still on treatment with vinblastine-sulfate the decanulement was possible, the patient could resume his profession as bassoonist. This successful treatment regimen has not been mentioned in the ENT-literature previously.
卡波西肉瘤累及耳鼻喉区域通常在皮肤发病数年之后才出现。因此,耳鼻喉文献中关于卡波西肉瘤的报道非常罕见。迄今为止,包括X射线照射在内的任何治疗方法都无法取得令人满意的效果。最近引入的硫酸长春碱长期治疗对于缩小肿瘤浸润的大小和范围非常有效。在耳鼻喉区域,腭、咽、喉和气管最常受累。我们报告了一名广泛累及咽和喉的患者,该患者不得不进行气管切开术。在仍接受硫酸长春碱治疗期间,拔管成为可能,患者能够重新从事巴松管演奏员的职业。这种成功的治疗方案此前在耳鼻喉文献中尚未被提及。