Tucker H M
Ann Otol Rhinol Laryngol. 1980 Nov-Dec;89(6 Pt 1):504-7. doi: 10.1177/000348948008900603.
A two-year-old female presented to the author with a 11/2 year history of multiple recurrences of juvenile laryngeal papillomatosis which when first seen had progressed to and below the tracheotomy site. The entire supraglottic larynx, glottis, and subglottic area were completely filled with exuberant papillomata. There was active growth of papilloma at and below the tracheotomy site and the tube had to be inserted through papilloma in order to reach a clear area in the trachea. In hopes of preventing further spread of papilloma below the area already involved and in order to control the airway and provide access to the subglottic area for laser removal, a double-barreled tracheostomy was performed. Laser treatment and/or spontaneous resolution ultimately resulted in complete clearing of all papillomata from the upper and lower tracheal segments. Four years and nine months after the initial procedure it was felt safe to attempt reconstruction. Her postoperative course was uneventful and she was successfully extubated three months later. Both vocal cords are normally mobile and her voice is quite clear although slightly hoarse as a result probably of slight changes in the edges of the cords because of the repeated surgical interventions. There has been no recurrence of papilloma now, over one year since reconstruction of the trachea. This somewhat radical approach to a life-threatening growth of endotracheal papilloma was successful in preventing further spread below the level of tracheostomy and ultimately permitted total reconstruction of an intact tracheal bronchial tree in the case reported.
一名两岁女童因幼年型喉乳头状瘤多次复发已1.5年,初诊时病情已发展至气管切开部位及以下。整个声门上喉、声门和声门下区域完全布满了大量乳头状瘤。气管切开部位及以下乳头状瘤生长活跃,气管插管必须穿过乳头状瘤才能进入气管内的通畅区域。为防止乳头状瘤在已累及区域以下进一步扩散,控制气道,并为激光切除声门下区域提供通路,实施了双腔气管造口术。激光治疗和/或自行消退最终使上下气管段的所有乳头状瘤完全清除。初次手术后四年零九个月,认为尝试重建是安全的。她术后恢复顺利,三个月后成功拔管。双侧声带活动正常,尽管由于反复手术干预,声带边缘可能略有变化,声音略显嘶哑,但她的声音相当清晰。自气管重建以来已过去一年多,目前乳头状瘤未复发。在该病例中,这种针对危及生命的气管内乳头状瘤生长的较为激进的方法成功地防止了其在气管切开水平以下的进一步扩散,并最终实现了完整气管支气管树的完全重建。