Barret-Connor E, Criqui M H, Klauber M R, Holdbrook M
Am J Epidemiol. 1981 Mar;113(3):276-84. doi: 10.1093/oxfordjournals.aje.a113097.
The relationship between diabetes and hypertension in 3456 residents of Rancho Bernardo, California, aged 50-79 years, surveyed in 1972-1974, was analyzed in depth in both the univariate mode and after adjustments for the potential confounding effects of age, obesity and diuretic medication. An association between diabetes and hypertension was present in both men and women at all ages, and the association was strongest for subjects having the best evidence for diabetes, i.e., both historical diabetes and fasting hyperglycemia. Adjustment for obesity reduced the association considerably, but a consistent association remained. diabetes and hypertension are linked only partially by obesity. Some of the excess risk of coronary heart disease in diabetes is probably due to hypertension.
对1972年至1974年期间在加利福尼亚州兰乔贝纳多市接受调查的3456名年龄在50至79岁之间的居民中糖尿病与高血压之间的关系,在单变量模式下以及在对年龄、肥胖和利尿剂药物的潜在混杂效应进行调整后进行了深入分析。糖尿病与高血压之间的关联在所有年龄段的男性和女性中均存在,并且对于具有最佳糖尿病证据的受试者,即既有既往糖尿病又有空腹血糖过高的受试者,这种关联最为强烈。对肥胖进行调整后,这种关联显著降低,但仍存在一致的关联。糖尿病和高血压仅部分地由肥胖联系起来。糖尿病中冠心病的一些额外风险可能归因于高血压。