Palma Gámiz J L, Calderón Montero A
Servicio de Cardiología, Hospital Ramón y Cajal, Madrid.
Rev Esp Cardiol. 1995;48 Suppl 4:57-65.
Ambulatory blood pressure monitoring (ABPM) is, nowadays, one of the most powerful medical tools, in the evaluation of blood pressure (BP) behaviour during a normal daily life, particularly in hypertensive patients, and to assess with a high level of accuracy, the antihypertensive effectiveness of the pharmacological compounds. In this paper, we present the main indications and limitations of the method, and a new circadian classification of arterial hypertension based on an average deviation index (ADI), resulting of the addition of all the systolic and diastolic ambulatory measurements exceeding 140/90 mmHg recorded along the 24-hour extrahospital monitoring, and dividing the result by two. The study was carried out in 939 hypertensive patients diagnosed by means of basal blood pressure measurements (BP > 140/90 mmHg), and in 45 normal volunteers. Hypothetically, this ADI may vary only from 0 (normal curve) to 100% (complete abnormal circadian curve). From ADI 0 to 100, we have established 4 categories of circadian curves as follows: curve 0 or "normal" if the ADI varies from 0 to 5%, curve type I or "borderline" (white coat phenomenon) if ADI moves between 6 and 30%, curve type II or "diurnal" if the ADI varies from 31 to 65%, and finally curve type III or "sustained", if the ADI goes further on than 66%. The results indicate clearly a high percentage of white coat hypertension (30%) where 4% showed an ADI less than 5%. A half approximately of the patients showed diurnal hypertension, and a quarter of them, both diurnal and nocturnal hypertension, so-called sustained hypertension. 75% of all the hypertensive patients showed spontaneous normotensive values at nighttime.(ABSTRACT TRUNCATED AT 250 WORDS)
如今,动态血压监测(ABPM)是最有效的医学工具之一,用于评估日常生活中的血压(BP)行为,尤其是高血压患者,并以高度准确性评估药物化合物的降压效果。在本文中,我们介绍了该方法的主要适应证和局限性,以及一种基于平均偏差指数(ADI)的新的高血压昼夜分类法。ADI是通过将24小时院外监测记录的所有收缩压和舒张压动态测量值超过140/90 mmHg的数值相加,再除以2得出的。该研究对9�9例通过基础血压测量确诊的高血压患者(BP>140/90 mmHg)和45例正常志愿者进行。假设该ADI仅可从0(正常曲线)变化至100%(完全异常昼夜曲线)。从ADI 0到100,我们建立了4类昼夜曲线如下:如果ADI在0至5%之间变化,则为曲线0或“正常”;如果ADI在6%至30%之间,则为I型曲线或“临界”(白大衣现象);如果ADI在31%至65%之间变化,则为II型曲线或“日间”;如果ADI超过66%,则为III型曲线或“持续”。结果清楚地表明白大衣高血压的比例很高(30%),其中4%的患者ADI小于5%。大约一半的患者表现为日间高血压,四分之一的患者表现为日间和夜间高血压,即所谓的持续性高血压。所有高血压患者中有75%在夜间出现自发性血压正常值。(摘要截断于250字)