使用芬苯达唑的分次给药/低剂量概念
The divided dosage/low dosage concept using fenbendazole.
作者信息
Gaenssler J G, Wilkins C A, O'Donnovan W M
出版信息
J S Afr Vet Assoc. 1978 Dec;49(4):345-9.
Fenbendazole was administered as an anthelmintic to cattle and sheep by incorporation into feed blocks. The therapeutic dose of 5 mg/kg live mass for sheep and 10 mg/kg for cattle was administered in divided dosages over periods of 4 d and in some cases 5 d. The periods were limited to obviate possible development of resistance. The anthelmintic effect was equal to, or better than, the standard therapeutic dose administered as a single dose in the form of the commercially available fenbendazole suspensions, when comparing the results obtained by the modified non-parametric method of evaluating anthelmintics.
通过将芬苯达唑混入饲料块中，作为驱虫药给牛和羊使用。绵羊的治疗剂量为每千克体重5毫克，牛为每千克体重10毫克，分剂量在4天内给药，某些情况下为5天。给药周期受到限制，以避免可能产生耐药性。当采用改良的非参数方法评估驱虫药的效果时，与以市售芬苯达唑悬浮液形式单次给药的标准治疗剂量相比，这种给药方式的驱虫效果相同或更好。
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