Crow S J, Mitchell J E
Department of Psychiatry, University of Minnesota, Minneapolis.
Drugs. 1994 Sep;48(3):372-9. doi: 10.2165/00003495-199448030-00004.
Pharmacological treatments are one of several strategies used in the treatment of anorexia nervosa and bulimia nervosa. Many studies have found that antidepressants are effective in the treatment of bulimia nervosa and these drugs represent a mainstay of treatment for these patients. Over the past several years, selective serotonin reuptake inhibitors have become perhaps the most commonly used class of drugs. A variety of medications have been investigated for anorexia nervosa, but there is little consistent evidence that medications are effective. In both these illnesses it is important to diagnose and treat any comorbid conditions including mood and anxiety disorders; this may involve the administration of other medications, including anxiolytics such as benzodiazepines or buspirone or mood stabilising agents such as lithium, valproic acid (valproate sodium) or carbamazepine.
药物治疗是用于治疗神经性厌食症和神经性贪食症的几种策略之一。许多研究发现,抗抑郁药对治疗神经性贪食症有效,这些药物是这些患者治疗的主要手段。在过去几年中,选择性5-羟色胺再摄取抑制剂可能已成为最常用的一类药物。针对神经性厌食症已对多种药物进行了研究,但几乎没有一致的证据表明药物有效。在这两种疾病中,诊断和治疗任何共病情况(包括情绪和焦虑障碍)都很重要;这可能涉及使用其他药物,包括苯二氮䓬类或丁螺环酮等抗焦虑药,或锂盐、丙戊酸(丙戊酸钠)或卡马西平等心境稳定剂。