Burns B J, Santos A B
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.
Psychiatr Serv. 1995 Jul;46(7):669-75. doi: 10.1176/ps.46.7.669.
Results of randomized clinical trials of assertive community treatment for seriously mentally ill patients published between 1990 and 1994 are reviewed to synthesize the state of knowledge about this research and to clarify continuing research directions.
Randomized trials of interventions that used treatment principles and practices consistent with the Program for Assertive Community Treatment model or close adaptations whose results were published since 1990 were identified by literature searches using MEDLINE and PsychLit and by contact with investigators of ongoing trials.
Controlled clinical trials have been conducted with a wide range of severely mentally ill populations, including patients in Great Britain, patients with recent-onset schizophrenia, veterans, dually diagnosed clients, and homeless persons. Methodological improvements in some studies include increased attention to monitoring the experimental and comparison interventions, as well as larger sample sizes and longer duration of the clinical trials than in earlier efficacy trials. Strong positive effects of assertive community treatment on hospital days and on patient and family satisfaction were found. Gains in functional outcomes, such as employment, may require interventions specifically targeted to these outcomes.
Questions about the role of assertive community treatment as time-limited treatment, as an adjunct to other services and treatment, or as a comprehensive and continuous service system for adults with severe mental illness require further research. The growing research base should provide valuable information on costs, outcomes, and indications for assertive community treatment that can be evaluated by policy-makers.
回顾1990年至1994年间发表的关于为严重精神疾病患者提供积极社区治疗的随机临床试验结果,以综合该研究的知识现状,并明确持续的研究方向。
通过使用MEDLINE和PsychLit进行文献检索,并与正在进行试验的研究人员联系,确定自1990年以来发表的使用与积极社区治疗模式一致的治疗原则和实践或紧密改编的干预措施的随机试验。
已针对广泛的严重精神疾病人群开展了对照临床试验,包括英国的患者、近期发病的精神分裂症患者、退伍军人、双重诊断患者和无家可归者。一些研究在方法上的改进包括更多地关注对实验性干预措施和对照干预措施的监测,以及与早期疗效试验相比更大的样本量和更长的临床试验持续时间。发现积极社区治疗对住院天数以及患者和家属满意度有强烈的积极影响。在功能结局方面的改善,如就业,可能需要专门针对这些结局的干预措施。
关于积极社区治疗作为限时治疗、作为其他服务和治疗的辅助手段或作为严重精神疾病成年人的全面持续服务系统的作用的问题,需要进一步研究。不断增加的研究基础应能提供关于积极社区治疗的成本、结局和适应症的有价值信息,供政策制定者评估。