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男性髋部骨折后生存率降低的决定因素。

Determinants of reduced survival following hip fractures in men.

作者信息

Poór G, Atkinson E J, O'Fallon W M, Melton L J

机构信息

Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

出版信息

Clin Orthop Relat Res. 1995 Oct(319):260-5.

PMID:7554638
Abstract

To assess determinants of poor survival after hip fractures in men, a population-based cohort study was conducted among 131 men in Rochester, MN, who had their first hip fracture during the period from 1978 to 1989, and an equal number of age-matched control men from the community. One hundred nine patients with fractures died during 373 person-years of followup, but only 75 control men died during 742 person-years of observation. The risk of dying increased with the level of comorbidity among hip fracture cases (hazard ratio 3.2; 95% confidence interval, 1.2-8.2), as well as with age (hazard ratio, 1.4 per 10-year increase; 95% confidence ratio, 1.1-1.8) and mental confusion during hospitalization (hazard ratio, 4.2; 95% confidence interval, 2.5-6.9). Discharge to a nursing home and low activity status also were predictors of death in the univariate analysis. Excess mortality among men with hip fractures can be explained best by interaction of the fracture with serious underlying medical conditions.

摘要

为评估男性髋部骨折后生存率低的决定因素,在明尼苏达州罗切斯特市对131名在1978年至1989年期间首次发生髋部骨折的男性以及相同数量的来自社区的年龄匹配对照男性进行了一项基于人群的队列研究。在373人年的随访期间,109名骨折患者死亡,但在742人年的观察期间,只有75名对照男性死亡。髋部骨折病例中,死亡风险随着合并症程度的增加而升高(风险比3.2;95%置信区间,1.2 - 8.2),同时也随着年龄增长(每增加10岁风险比为1.4;95%置信区间,1.1 - 1.8)以及住院期间精神错乱情况(风险比4.2;95%置信区间,2.5 - 6.9)而升高。在单因素分析中,出院后入住疗养院以及活动水平低也是死亡的预测因素。髋部骨折男性的额外死亡率最好通过骨折与严重基础疾病的相互作用来解释。

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