Konter U, Pape H D, Tirpitz D, Schippers C
Klinik und Poliklinik für Zahn-, Mund-, und Kieferheilkunde der Universität, Mund-, Kiefer- und Gesichtschirurgie, Köln.
Fortschr Kiefer Gesichtschir. 1995;40:160-2.
In spite of preventive procedures before, during and after radiotherapy, profound caries and periodontal breakdown of healthy teeth occur. In the course of dentoalveolar surgery in the region of irradiated bone, the risk of development of an infected osteoradionecrosis can be reduced by prophylactic antibodies, prevention of extensive detaching of the periosteum careful osteotomy or extraction, complete smoothing of sharp alveolar ridges and epiperiosteal plastic coverage. When extensive dentoalveolar surgery is necessary, the application of prophylactic pre- and postoperative hyperbaric oxygen may reduce the rate of complications even more.
尽管在放疗前、放疗期间和放疗后采取了预防措施,但健康牙齿仍会出现严重龋齿和牙周破坏。在受照射骨区域进行牙槽外科手术时,预防性使用抗体、防止骨膜广泛剥离、谨慎进行截骨术或拔牙、彻底打磨尖锐的牙槽嵴以及骨膜上整形覆盖等措施可降低感染性放射性骨坏死的发生风险。当需要进行广泛的牙槽外科手术时,术前和术后应用预防性高压氧可能会进一步降低并发症发生率。