The role of total thyroidectomy in the management of differentiated thyroid cancer.

The extent of surgical resection required in the optimal management of differentiated (papillary and follicular) thyroid carcinoma remains controversial. Arguments in favor of total thyroidectomy include the adequate treatment of tumor multifocality, reduction in local recurrence rates and anaplastic transformation, and creating a suitable environment for radioactive iodine scanning and treatment of metastases. The benefits of this procedure have to be weighed against the potential but minimal morbidity.