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一例罕见的交感神经维持性面部疼痛合并毛细血管扩张症病例。

An unusual case of sympathetically maintained facial pain complicated by telangiectasia.

作者信息

Saxen M A, Campbell R L

机构信息

Department of Diagnostic Sciences, Indiana University School of Dentistry, Indianapolis 46202-5186, USA.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Apr;79(4):455-8. doi: 10.1016/s1079-2104(05)80127-1.

Abstract

A 32-year-old woman with a history of maxillary sinusitis, multiple surgical interventions in the maxillary sinus, and a hyperalgesic, erythematous skin lesion in her left infraorbital area, had severe burning pain in the left face. The dermal lesion was diagnosed as atypical telangiectasia and the sinus pathoses determined to be unrelated to her symptoms. Two diagnostic stellate ganglion blocks were performed with concurrent bilateral monitoring of blood flow in the infraorbital skin. Blood flow was significantly increased in the painful erythematous patch although no significant change in flow occurred in the unaffected contralateral skin. The changes correlated to patient's relief from pain. The patient's symptoms were subsequently controlled with an oral sympatholytic agent. This article demonstrates the usefulness of laser doppler flowmetry to establish the diagnosis of sympathetically maintained facial pain despite several confounding conditions and supports the theory that sympathetically maintained pain involves altered function of alpha-1 adrenoreceptors.

摘要

一名32岁女性,有上颌窦炎病史,曾多次接受上颌窦手术,左侧眶下区域有痛觉过敏的红斑性皮肤病变,左侧面部有严重灼痛。皮肤病变被诊断为非典型毛细血管扩张,鼻窦病变被确定与她的症状无关。进行了两次诊断性星状神经节阻滞,同时对眶下皮肤的血流进行双侧监测。尽管未受影响的对侧皮肤血流没有明显变化,但疼痛性红斑部位的血流显著增加。这些变化与患者疼痛缓解相关。患者的症状随后通过口服抗交感神经药得到控制。本文证明了激光多普勒血流仪在尽管存在多种混淆情况时仍有助于诊断交感神经维持性面部疼痛,并支持交感神经维持性疼痛涉及α-1肾上腺素能受体功能改变这一理论。

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