Siegel S B, White G H, Colman P D, Nelson R J
Department of Surgery, Harbor-UCLA Medical Center, Torrance, USA.
J Card Surg. 1995 May;10(3):210-20. doi: 10.1111/j.1540-8191.1995.tb00601.x.
Despite advances in coronary artery surgery, technical abnormalities remain a significant cause of early graft closure. The development of small fiberoptic angioscopes now allows direct intravascular magnified examination. Seventy-five distal anastomoses and vein grafts, and five selected coronary arteries were examined with 0.8- to 2.5-mm diameter angioscopes introduced through the proximal vein graft while irrigating with clear cardioplegia. Angioscopic findings were correlated with angiographic data, vessel morphology, graft flow, and postoperative course. Satisfactory images were obtained in 72 of 75 anastomotic inspections. Each examination took less than 2 minutes and required less than 100 cc of flush. Angioscopic abnormalities that did not require revision were noted in 17 of 72 anastomoses; intimal flaps in 9, thrombus on posterior wall plaque in 4, intimal irregularities in 4, bucking of posterior wall in 3, and valve near anastomoses in 1. No outflow obstruction nor misplaced sutures were noted. Average flow rate through the grafts with anastomotic angioscopic abnormalities was 33 cc/min versus 40 cc/min in the remaining grafts. However, regression analysis revealed that low-graft flow was correlated with vessel size and runoff but was not with angioscopic findings. Intracoronary angioscopy revealed discrepancy with angiographic findings in 4 of the 5 examinations. No complications occurred as a result of angioscopy. No graft closure has occurred during early follow-up. Intraoperative angioscopy can be done with minimal alteration of the usual routine. The 24% occurrence of minor angioscopic abnormalities did not appear to compromise graft flow or early patency.
尽管冠状动脉手术取得了进展,但技术异常仍是早期移植物闭塞的重要原因。小型光纤血管镜的发展使得直接进行血管内放大检查成为可能。通过近端静脉移植物插入直径为0.8至2.5毫米的血管镜,在灌注清亮心脏停搏液的同时,对75个远端吻合口和静脉移植物以及5条选定的冠状动脉进行了检查。血管镜检查结果与血管造影数据、血管形态、移植物血流及术后病程相关。75次吻合口检查中有72次获得了满意的图像。每次检查耗时不到2分钟,冲洗液用量不到100毫升。72次吻合口中有17次发现了无需修正的血管镜异常;9次出现内膜瓣,4次在后壁斑块上有血栓,4次内膜不规则,3次后壁凸起,1次在吻合口附近有瓣膜。未发现流出道梗阻或缝线位置不当。吻合口有血管镜异常的移植物平均流速为33毫升/分钟,其余移植物为40毫升/分钟。然而,回归分析显示,低移植物血流与血管大小和侧支循环有关,与血管镜检查结果无关。冠状动脉内血管镜检查在5次检查中有4次显示与血管造影结果存在差异。血管镜检查未引发并发症。早期随访期间未发生移植物闭塞。术中血管镜检查可在对常规操作改动最小的情况下完成。24%的轻微血管镜异常发生率似乎并未影响移植物血流或早期通畅率。