Protein design: novel metal-binding sites.
作者信息
Regan L
机构信息
Yale University Department of Molecular Biophysics and Biochemistry, New Haven, CT 06520, USA.
出版信息
Trends Biochem Sci. 1995 Jul;20(7):280-5. doi: 10.1016/s0968-0004(00)89044-1.
PMID:7667881
Abstract
In natural proteins, metal ions play a variety of roles, including nucleophilic catalysis, electron transfer and the stabilization of protein structure. The de novo design of metal-binding sites is therefore an attractive means by which to impart proteins with novel properties and activities.
摘要
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