Gaertner E, Simon P, Pottecher T
Service d'Anesthésie et de Réanimation chirurgicale, Hôpital de Hautepierre, Strasbourg.
Cah Anesthesiol. 1995;43(1):35-41.
Fat embolism is a severe complication in patients with femoral fractures. This retrospective study records 17 cases of post traumatic fat embolism diagnosed between 1979 and 1993 among 430 patients admitted for femoral fractures (incidence: 2.7%). These cases underline the high frequency of early hypovolaemia (10/17), of respiratory and cerebral disorders (15/17), all occurring during the first post trauma week. Three cases were observed in the postoperative period. Severity of fat embolism is proved by three deaths and a mean mechanical ventilation period of 13 days. With early osteosynthesis, incidence of fat embolism could be lowered to 0.2%. Prevention is based on osteosynthesis, avoidance of hypovolemia and of hypoalbuminemia.
脂肪栓塞是股骨骨折患者的一种严重并发症。这项回顾性研究记录了1979年至1993年间在430例因股骨骨折入院的患者中诊断出的17例创伤后脂肪栓塞病例(发病率:2.7%)。这些病例突显了早期低血容量(10/17)、呼吸和脑部疾病(15/17)的高发生率,所有这些都发生在创伤后的第一周内。术后观察到3例。3例死亡以及平均机械通气时间为13天证明了脂肪栓塞的严重性。通过早期骨固定,脂肪栓塞的发病率可降至0.2%。预防措施基于骨固定、避免低血容量和低白蛋白血症。