Antiphospholipid antibody syndrome: a new cause of nonhealing skin ulcers.

Antiphospholipid antibody syndrome causes many problems that are usually treated by rheumatologists. Included within the manifestations of the syndrome, however, are painful, refractory leg ulcers, which, with the causative vascular damage, may lead to limb loss. The report of such a case, the patient's course and treatment, and the causes and diagnosis of the syndrome are presented.