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来自瑞士的线粒体DNA序列揭示了欧洲人群惊人的同质性。

Mitochondrial DNA sequences from Switzerland reveal striking homogeneity of European populations.

作者信息

Pult I, Sajantila A, Simanainen J, Georgiev O, Schaffner W, Pääbo S

机构信息

Institut für Molekularbiologie II, Universität Zürich, Switzerland.

出版信息

Biol Chem Hoppe Seyler. 1994 Dec;375(12):837-40.

PMID:7710701
Abstract

Mitochondrial DNA sequences from 74 Swiss individuals were compared to sequences from British and Finish populations. We found that the nucleotide sequence differences between these populations are almost as low as those within the populations. This is in contrast to three African populations, which display substantial differences between each other. The homogeneity of the mitochondrial gene pool in Europe suggests a recent common ancestry for European populations. This may reflect the arrival of anatomically modern humans about 40,000-30,000 years ago or, alternatively, the spread of agriculturalists about 10,000-6,000 years ago. Taking into account the estimated rate of evolution of the mitochondrial control region, the data favor the former explanation.

摘要

对74名瑞士人的线粒体DNA序列与英国人和芬兰人群体的序列进行了比较。我们发现,这些群体之间的核苷酸序列差异几乎与群体内部的差异一样低。这与三个非洲群体形成对比,这三个非洲群体彼此之间存在显著差异。欧洲线粒体基因库的同质性表明欧洲人群体有较近的共同祖先。这可能反映了约4万至3万年前解剖学上现代人类的到来,或者另一种情况是,约1万至6千年前农业人群的扩散。考虑到线粒体控制区的估计进化速率,数据支持前一种解释。

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