Adam M C, Tribouilloy C, Mirode A, Rey J L, Bickert P, Lesbre J P
Service de Cardiologie, Centre Hospitalier, Beauvais.
Presse Med. 1995 Mar 11;24(10):479-82.
Among a series of 6 patients who had paradoxical emboli after pulmonary embolus, thrombus was encrusted in the foramen ovale in 2 while contrast echocardiography showed a free foramen ovale in the 4 others. Surgical embolectomy was performed in 1 of the patients with a thrombus in the foramen ovale. This patient died in the post-operative period and the second patient died suddenly before the indication for surgery had been established. The 4 other patients were treated medically with anticoagulant therapy. After a follow-up of 37, 33, 32 and 3 months respectively none of these patients has developed recurrent emboli. The association of a thromboembolic disease and a systemic ischaemic event should strongly suggest the diagnosis of paradoxical embolus. Echocardiography is required to determine whether the foramen ovale is free or harbours a thrombus.
在一系列6例肺栓塞后发生反常栓塞的患者中,2例卵圆孔内有血栓形成,另4例经对比超声心动图显示卵圆孔开放。1例卵圆孔内有血栓的患者接受了手术取栓。该患者术后死亡,另1例患者在确定手术指征前突然死亡。其他4例患者接受了抗凝药物治疗。分别随访37、33、32和3个月后,这些患者均未发生复发性栓塞。血栓栓塞性疾病与全身性缺血事件同时出现应强烈提示反常栓塞的诊断。需要超声心动图来确定卵圆孔是开放的还是有血栓。