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["青铜色婴儿"综合征]

["Bronze baby" syndrome].

作者信息

Rodot S, Lacour J P, Dageville C, Castanet J, Boutté P, Ortonne J P

机构信息

Service de Dermatologie, Hôpital Pasteur, Nice.

出版信息

Ann Dermatol Venereol. 1994;121(8):568-70.

PMID:7755316
Abstract

"Bronze baby" syndrome is a rare complication of phototherapy for neonatal jaundice occurring due to modified liver function, particularly cholestasis, of various origins. We report a case which occurred in a premature infant who developed a grey-brown coloration during phototherapy. The infant had haemolytic jaundice due to Rhesus incompatibility complicated by cholestasis of thick bile fluid. Abnormal accumulation of unexcreted photoproducts due to the cholestasis appeared to be the cause of the bronze coloration. The clinical course was favourable and the skin coloration returned to normal a few weeks after the end of the phototherapy. It is essential to identify the underlying liver disease in order to determine the prognosis of this syndrome.

摘要

“青铜宝宝”综合征是新生儿黄疸光疗的一种罕见并发症,其发生是由于各种原因导致肝功能改变,尤其是胆汁淤积。我们报告一例发生在早产儿的病例,该患儿在光疗期间出现灰棕色皮肤。患儿因Rh血型不合导致溶血性黄疸,并伴有浓稠胆汁液胆汁淤积。胆汁淤积导致未排泄的光产物异常蓄积,这似乎是皮肤青铜色的原因。临床过程良好,光疗结束几周后皮肤颜色恢复正常。识别潜在的肝脏疾病对于确定该综合征的预后至关重要。

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