Gaffney B, Kee F
Department of Public Health Medicine, Eastern Health and Social Services Board, Belfast.
Br Heart J. 1995 Apr;73(4):385-9. doi: 10.1136/hrt.73.4.385.
To investigate the possibility of an association between the duration of medical treatment before coronary angiography and demographic and non-clinical factors.
A systematic review of a random sample of 500 patients undergoing their first angiographic assessment.
500 cases were selected randomly from patients investigated in 1991 at the two catheterisation centres in Northern Ireland.
The duration of medical management before angiography.
346 had elective and 154 urgent catheterisation. The duration of medical management was adjusted for both case mix (age at onset, body mass index, angina grade, history of myocardial infarction, history of hypertension, diabetes or hyperlipidaemia, treatment intensity) and other demographic variables (sex, smoking status, an indicator of "deprivation", and distance of the patient's area of residence from the hospital). After this adjustment the mean duration of medical management before angiography was twice as long for economically inactive patients as for those who were economically active. In a multiple regression, the relevant beta coefficient was 0.44 (95% confidence interval 0.33 to 0.58, P < 0.0001).
These results suggest that, in making discretionary decisions about when to refer patients with angina for revascularisation assessment, doctors may be influenced by non-clinical factors unrelated to disease severity.
探讨冠状动脉造影前药物治疗时长与人口统计学及非临床因素之间存在关联的可能性。
对500例接受首次血管造影评估的患者随机样本进行系统评价。
从1991年在北爱尔兰两个导管插入中心接受检查的患者中随机选取500例。
血管造影前药物治疗的时长。
346例为择期导管插入术,154例为紧急导管插入术。针对病例组合(发病年龄、体重指数、心绞痛分级、心肌梗死病史、高血压、糖尿病或高脂血症病史、治疗强度)及其他人口统计学变量(性别、吸烟状况、“贫困”指标以及患者居住地区与医院的距离)对药物治疗时长进行了调整。调整后,无经济活动能力患者血管造影前药物治疗的平均时长是有经济活动能力患者的两倍。在多元回归分析中,相关β系数为0.44(95%置信区间0.33至0.58,P<0.0001)。
这些结果表明,在酌情决定何时将心绞痛患者转诊进行血运重建评估时,医生可能会受到与疾病严重程度无关的非临床因素的影响。