Schröter R, Bersch A, Osswald F
Z Hautkr. 1975 Aug 1;50(15):637-56.
Five female patients with benign gonococcal sepsis were seen during the second half of 1974. All cases presented the typical clinical triad of fever, arthralgias and characteristic skin lesions, the macroscopic and microscopic appearance of which could be best classified as superficial vasculitis. Skin biopsies were taken from 3 patients and the histopathological findings are discussed in detail. Genital symptoms were slight or absent, and only very few gonococci could be detected in stained smears from genital sites. However, Neisseria gonorrhoeae could be cultured without difficulty from the genitourinary tract in all cases, while cultures from blood and skin lesions were sterile. In fresh pustules gonococci could be demonstrated by immunofluorescence in 2 cases. The complement-fixation-test is regarded as a useful supplementary diagnostic procedure.
1974年下半年,共诊治了5例女性淋菌性败血症患者。所有病例均表现出典型的临床三联征,即发热、关节痛和特征性皮肤病变,其大体和显微镜下表现最宜归类为浅表性血管炎。对3例患者进行了皮肤活检,并对组织病理学检查结果进行了详细讨论。生殖器症状轻微或无,在生殖器部位的染色涂片中仅能检测到极少数淋球菌。然而,所有病例均能从泌尿生殖道轻松培养出淋病奈瑟菌,而血液和皮肤病变部位的培养物均无菌。在2例新鲜脓疱中,通过免疫荧光法可检测到淋球菌。补体结合试验被认为是一种有用的辅助诊断方法。