Kretzschmar L, Bonsmann G, Metze D, Luger T A, Schwarz T
Universitäts-Hautklinik, Münster.
Hautarzt. 1995 Mar;46(3):154-7. doi: 10.1007/s001050050229.
Temporary hair loss is well accepted as a possible result of psoriatic plaques. On the other hand, it is still a controversial issue whether psoriasis can cause scarring alopecia. The following report presents a 38-year-old woman who had been suffering from progressive hair loss from chronic psoriatic plaques of the scalp for some years. Clinical examination revealed an area of scarring alopecia in association with typical features of psoriasis. Histology showed a cord-like fibrosis replacing former hair follicles, a perivascular lymphohistiocytic infiltrate in the upper dermis occasionally invading the follicular epithelium, and characteristic features of psoriasis of the scalp. The clinical course and the lack of evidence for any other causes of scarring alopecia suggest an aetiopathogenetic link between psoriasis and scarring alopecia. Knowledge of this relationship appears to be of practical significance, since efficient antipsoriatic therapy can stop hair loss and thus may be able to prevent scarring.
暂时性脱发被广泛认为是银屑病斑块可能导致的结果。另一方面，银屑病是否会引起瘢痕性脱发仍是一个有争议的问题。以下报告介绍了一名38岁女性，她因头皮慢性银屑病斑块而遭受渐进性脱发数年。临床检查发现一处瘢痕性脱发区域，并伴有银屑病的典型特征。组织学检查显示条索状纤维化取代了先前的毛囊，真皮上层血管周围有淋巴细胞和组织细胞浸润，偶尔侵犯毛囊上皮，以及头皮银屑病的特征性表现。临床病程以及缺乏瘢痕性脱发其他病因的证据表明银屑病与瘢痕性脱发之间存在病因学联系。了解这种关系似乎具有实际意义，因为有效的抗银屑病治疗可以阻止脱发，从而可能预防瘢痕形成。
