来自中华石荠苎的三萜皂苷。

Triterpenoid saponins from Clinopodium chinensis.

作者信息

Liu Z, Jia Z, Cates R G, Li D, Owen N L

机构信息

State Key Laboratory of Applied Organic Chemistry, Lanzhou University, People's Republic of China.

出版信息

J Nat Prod. 1995 Feb;58(2):184-8. doi: 10.1021/np50116a004.

DOI:10.1021/np50116a004

PMID:7769387

Abstract

Two new triterpenoid saponins, 3 beta,16 beta,23-trihydroxy-13,28-epoxyolean- 11-en-3-yl-[beta-D-glucopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->3)]- [beta-D-glucopyranosyl(1-->2)]-beta-D-fucopyranoside[1](clinopodiside B) and 28-O-beta-D-glucopyranosyl-3 beta,23-dihydroxyoleana-12,21-dien-3-yl-beta-D-glucopyranosy l-(1-->3)-beta-D- fucopyranoside [3] (clinopodiside C), together with three known saikosaponins, buddlejasaponins IV, IVa, and IVb, have been isolated from the plant, Clinopodium chinensis, and characterized using chemical evidence and spectroscopic methods, in particular 2D nmr spectroscopy.

摘要

从中华石蚕（Clinopodium chinensis）中分离出了两种新的三萜皂苷，即3β,16β,23 - 三羟基 - 13,28 - 环氧齐墩果 - 11 - 烯 - 3 - 基 - [β - D - 吡喃葡萄糖基(1→4)-β - D - 吡喃葡萄糖基(1→3)] - [β - D - 吡喃葡萄糖基(1→2)] - β - D - 岩藻糖苷[1]（石蚕苷B）和28 - O - β - D - 吡喃葡萄糖基 - 3β,23 - 二羟基齐墩果 - 12,21 - 二烯 - 3 - 基 - β - D - 吡喃葡萄糖基 - (1→3)-β - D - 岩藻糖苷[3]（石蚕苷C），同时还分离出了三种已知的柴胡皂苷，即醉鱼草皂苷IV、IVa和IVb，并通过化学证据和光谱方法，特别是二维核磁共振光谱对其进行了表征。