Cheirif J, Meza M, Murgo J P
Department of Cardiology, Ochsner Medical Institutions, New Orleans, Louisiana 70121, USA.
Tex Heart Inst J. 1995;22(1):33-9.
As investigators have discovered that cardiac regions displaying resting wall motion abnormalities are not the necessary equivalent of myocardial scar (and therefore of irreversible injury) but are potentially viable regions rendered dysfunctional by stunning or hibernation, a new field of medicine has developed to identify viable myocardium that can improve in function after revascularization. Moreover, improvements in myocardial preservation and perfusion during coronary artery bypass grafting and percutaneous transluminal coronary angioplasty have enabled patients with poor resting ejection fractions to undergo safer revascularization. In this review, we describe briefly the diagnostic techniques most commonly used in identifying dysfunctional but viable myocardium. We give specific attention to the assets and limitations of these techniques and special emphasis to 2 promising new techniques: dobutamine echocardiography and myocardial contrast echocardiography.
由于研究人员发现,显示静息壁运动异常的心脏区域不一定等同于心肌瘢痕(因此也不一定等同于不可逆损伤),而是可能因心肌顿抑或冬眠而功能失调的存活区域,一个新的医学领域应运而生,旨在识别血管重建后功能可改善的存活心肌。此外,冠状动脉旁路移植术和经皮冠状动脉腔内血管成形术中心肌保护和灌注的改善,使静息射血分数低的患者能够接受更安全的血管重建。在本综述中,我们简要描述了识别功能失调但存活心肌最常用的诊断技术。我们特别关注这些技术的优点和局限性,并特别强调两种有前景的新技术:多巴酚丁胺超声心动图和心肌对比超声心动图。