Marra G, Barbieri G, Moioli C, Assael B M, Grumieri G, Caccamo M L
Department of Paediatrics, University of Milan Medical School, Italy.
Arch Dis Child Fetal Neonatal Ed. 1994 Mar;70(2):F147-9; discussion 149-50. doi: 10.1136/fn.70.2.f147.
The management of neonates with mild hydronephrosis diagnosed antenatally is still debated. Although some of these infants are normal, it is recognised that others will have mild obstruction of the ureteropelvic junction or vesicoureteric reflux (VUR). A prospective study was performed in all newborn infants with an antenatal diagnosis of mild hydronephrosis (47 babies, 62 kidneys) born over a two year period in order to assess the frequency of VUR. Voiding cystography in 14 patients with 21 renal units showed VUR. Two patients underwent surgery and the VUR resolved; the other 12 received medical treatment. Repeat cystography was scheduled for 12-18 months later, when a high rate of spontaneous cure was observed. The remaining patients were monitored by ultrasonography but only in one case did hydronephrosis deteriorate because of the presence of severe ureteropelvic junction obstruction. It is concluded that mild dilatation of the pelvis might be an expression of a potentially severe malformation such as VUR, and a careful follow up of these cases is mandatory.
产前诊断为轻度肾积水的新生儿的管理仍存在争议。虽然其中一些婴儿是正常的,但人们认识到其他婴儿会有输尿管肾盂连接部轻度梗阻或膀胱输尿管反流(VUR)。对在两年期间出生的所有产前诊断为轻度肾积水的新生儿(47名婴儿,62个肾脏)进行了一项前瞻性研究,以评估VUR的发生率。14例患者的21个肾单位进行排尿膀胱造影显示有VUR。2例患者接受了手术,VUR得到缓解;其他12例接受了药物治疗。计划在12 - 18个月后进行重复膀胱造影,此时观察到自发治愈率很高。其余患者通过超声检查进行监测,但只有1例因存在严重的输尿管肾盂连接部梗阻而导致肾积水恶化。结论是肾盂轻度扩张可能是诸如VUR等潜在严重畸形的一种表现,对这些病例进行仔细随访是必要的。