Tragnone A, Valpiani D, Miglio F, Elmi G, Bazzocchi G, Pipitone E, Lanfranchi G A
Division of Internal Medicine, Bellaria Hospital, University of Bologna, Italy.
Eur J Gastroenterol Hepatol. 1995 Jan;7(1):47-51.
To examine the influence of dietary factors in Italian patients with ulcerative colitis and Crohn's disease.
We studied dietary habits immediately prior to the onset of disease in 104 patients enrolled in a prospective, epidemiological study of the incidence of inflammatory bowel disease in Italy.
Each patient was interviewed using a recall questionnaire to provide information on the daily intake of nutrients. The differences in diet between patients and healthy subjects matched for age, sex and city of residence were determined.
Our data confirm that patients with Crohn's disease and ulcerative colitis have a high intake of total carbohydrate, starch and refined sugar. This resulted in a significantly higher relative risk (P < 0.001) in both ulcerative colitis and Crohn's disease patients. Total protein intake was significantly higher in ulcerative colitis, but not in Crohn's disease patients, than in controls. Fibre consumption did not differ between patients and controls.
Our results confirm that carbohydrate consumption is significantly higher in IBD patients than in healthy controls. Ulcerative colitis patients also consumed more total protein than controls. The pathogenetic significance of these findings, however, remains unclear.
研究饮食因素对意大利溃疡性结肠炎和克罗恩病患者的影响。
我们对104名参与意大利炎症性肠病发病率前瞻性流行病学研究的患者在疾病发作前的饮食习惯进行了研究。
使用回顾性调查问卷对每位患者进行访谈，以获取有关每日营养素摄入量的信息。确定患者与年龄、性别和居住城市相匹配的健康受试者之间的饮食差异。
我们的数据证实，克罗恩病和溃疡性结肠炎患者的总碳水化合物、淀粉和精制糖摄入量较高。这导致溃疡性结肠炎和克罗恩病患者的相对风险显著更高（P < 0.001）。溃疡性结肠炎患者的总蛋白质摄入量显著高于对照组，但克罗恩病患者与对照组无差异。患者与对照组之间的纤维摄入量无差异。
我们的结果证实，炎症性肠病患者的碳水化合物摄入量显著高于健康对照组。溃疡性结肠炎患者的总蛋白质摄入量也高于对照组。然而，这些发现的致病意义仍不清楚。
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