一种用于分析酵母（酿酒酵母）交配中双倍体形成频率的概率方法。

A probabilistic approach to the analysis of the frequency of diploid formation in yeast (Saccharomyces cerevisiae) mating.

作者信息

Kopociński B, Lachowicz T M

机构信息

Mathematical Institute, Wrocław University, Poland.

出版信息

Mikrobiol Z. 1994 Nov-Dec;56(6):3-16.

PMID:7894727

Abstract

Conditions of optimizing mating efficiency in the yeast. Saccharomyces cerevisiae were tested and measured as a number of prototrophic diploids. It was found that the process of diploid formation could be controlled by suitably adjusting cell densities in liquid mating medium and alpha: a mating type cell ratio. When the first was about 5 x 10(8) per ml and the second 1:10, respectively, every alpha cell was able to find a partner of opposite mating type. Some mathematical models of the "courtship" in yeast were advanced and the conclusions are discussed in the light of recent data on mating pathway in S. cerevisiae.

摘要

对酿酒酵母中优化交配效率的条件进行了测试，并以原养型二倍体的数量进行了测量。结果发现，通过适当调整液体交配培养基中的细胞密度和α:a交配型细胞比例，可以控制二倍体形成的过程。当每毫升中第一个细胞密度约为5×10⁸且第二个比例为1:10时，每个α细胞都能找到一个相反交配型的伴侣。提出了酵母中“求偶”的一些数学模型，并根据酿酒酵母交配途径的最新数据对这些结论进行了讨论。