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在C57BL/6J小鼠中发现的一种新的睾丸女性化突变。

A new testicular feminization mutation found in C57BL/6J mice.

作者信息

Tanaka S, Kaneko T, Moriyama T, Matsuzawa A

机构信息

Laboratory Animal Research Center, University of Tokyo, Japan.

出版信息

Lab Anim. 1994 Jul;28(3):262-4. doi: 10.1258/002367794780681679.

Abstract

A new testicular feminization (Tfm) mutation found in the inbred strain of mice, C57BL/6JJms, was separated from the original line and established as a mutant strain. This line was named C57BL/6JJms-TfmJms. The process of discovery and breeding are described. Body weights were compared among male, normal virgin female and Tfm mice between 5 and 40 weeks of age. Tfm mice were generally intermediate in weight between male and virgin female mice. This result is different from that previously reported for the Tfm mouse strains and may be of interest in comparison between Tfm mice and their normal litter mates.

摘要

在近交系小鼠C57BL/6JJms中发现的一种新的睾丸雌性化(Tfm)突变体,从原品系中分离出来并培育成一个突变品系。该品系被命名为C57BL/6JJms-TfmJms。文中描述了发现和培育的过程。比较了5至40周龄的雄性、正常未交配雌性和Tfm小鼠的体重。Tfm小鼠的体重一般介于雄性和未交配雌性小鼠之间。这一结果与先前报道的Tfm小鼠品系不同,可能有助于比较Tfm小鼠与其正常同窝小鼠。

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Residual androgen binding in testicular feminization (TFM).睾丸女性化(TFM)中的残余雄激素结合
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