Karademir S, Demirçeken F, Atalay S, Demircin G, Sipahi T, Teziç T
Doctor Sami Ulus Children's Hospital, Ankara, Turkey.
Acta Paediatr. 1994 Aug;83(8):862-5. doi: 10.1111/j.1651-2227.1994.tb13158.x.
Two hundred and twenty-eight patients with acute rheumatic fever (ARF), who were admitted to Dr Sami Ulus Children's Hospital between January 1990 and November 1992, were evaluated. Compared with the 1980s, an increase in the frequency of the disease was observed. The majority of patients (56.5%) were between 9 and 12 years old and 36.8% were admitted in winter. One hundred patients had arthritis only, 59 carditis and 40 chorea; 5 had carditis and chorea and 24 had arthritis and carditis. Nineteen percent of patients had a history of a previous attack. Seven of 84 patients with carditis had congestive heart failure and 2 had pericarditis. Cardiomegaly was present in 36 patients. The mitral valve was affected in 77 patients, tricuspid valve in 1 patient and both miral and aortic valves in 6 patients. One patient died as a result of severe congestive cardiac failure. Twenty-one patients had a recurrent attack. We observed that ARF is still a significant cause of morbidity in our country. As the disease is preventable by the eradication of streptococcus, we conclude that more effort should be made in the early detection and treatment of streptococcal infections.
对1990年1月至1992年11月期间收治于萨米·乌卢斯儿童医院的228例急性风湿热（ARF）患者进行了评估。与20世纪80年代相比，观察到该病的发病率有所增加。大多数患者（56.5%）年龄在9至12岁之间，36.8%的患者在冬季入院。100例患者仅有关节炎，59例有心脏炎，40例有舞蹈病；5例有心脏炎和舞蹈病，24例有关节炎和心脏炎。19%的患者有既往发作史。84例心脏炎患者中有7例发生充血性心力衰竭，2例有心肌炎。36例患者存在心脏扩大。77例患者二尖瓣受累，1例三尖瓣受累，6例二尖瓣和主动脉瓣均受累。1例患者因严重充血性心力衰竭死亡。21例患者复发。我们观察到ARF在我国仍是发病的一个重要原因。由于该病可通过根除链球菌来预防，我们得出结论，应在链球菌感染的早期检测和治疗方面做出更多努力。
