Hippke W E, Blasum C P, Barth J
Klinik für Hautkrankheiten, Medizinische Fakultät Carl Gustav Carus, Technischen Universität, Dresden.
Hautarzt. 1994 Oct;45(10):711-5. doi: 10.1007/s001050050155.
Adult-onset Still's disease (AOSD) is a rare syndrome of unknown origin consisting of recurrent fever, urticarial rash, arthralgias or arthritides, lymphadenopathia, splenomegalia and nonspecific sore throat. It is always linked with leucocytosis and negative blood cultures; rheumatic and antinuclear factors are mostly negative. Very high ferritin levels are frequent and could be a marker of the disease. We report on two cases and give a review of the literature.
成人斯蒂尔病(AOSD)是一种病因不明的罕见综合征,其特征包括反复发热、荨麻疹样皮疹、关节痛或关节炎、淋巴结病、脾肿大以及非特异性咽痛。它常与白细胞增多和血培养阴性相关;风湿因子和抗核因子大多为阴性。铁蛋白水平经常非常高,可能是该疾病的一个标志物。我们报告两例病例并对文献进行综述。