磁共振成像在评估多发性硬化症临床试验中的应用

Magnetic resonance imaging in the evaluation of clinical trials in multiple sclerosis.

作者信息

Paty D W, Li D K, Oger J J, Kastrukoff L, Koopmans R, Tanton E, Zhao G J

机构信息

Department of Medicine, University of British Columbia, Vancouver, Canada.

出版信息

Ann Neurol. 1994;36 Suppl:S95-6. doi: 10.1002/ana.410360721.

DOI:10.1002/ana.410360721

PMID:8017896

Abstract

Magnetic resonance imaging (MRI) provides an objective method of evaluating multiple sclerosis clinical trials and is at least five times more sensitive to disease activity. In a recent clinical trial, MRI was also approximately twice as sensitive as clinical measurements to the treatment effect of a drug.

摘要

磁共振成像（MRI）为评估多发性硬化症临床试验提供了一种客观方法，并且对疾病活动的敏感度至少高出五倍。在最近的一项临床试验中，MRI对一种药物治疗效果的敏感度也大约是临床测量的两倍。