Morimoto T, Sasa M, Yamaguchi T, Harada K, Kondo H, Kuroda R
School of Medical Sciences, University of Tokushima.
Gan To Kagaku Ryoho. 1994 Jun;21 Suppl 2:158-63.
A mass screening trial for breast cancer using mammography was carried out in Tokushima Prefecture, either itinerant screening in the communities or center screening at the workplace. Craniocaudal and lateral oblique imagings of the breast using two-view film mammography were performed at the first stage of screening. In addition, physical examination of the breast was also performed on subjects independently. A total of 8 cases with breast cancer were found in these trials by mammography alone, and no cases with breast cancer were detected by physical examination. The detection rates were 0.19% in itinerant screening, and 0.92% in center screening, respectively. This was much higher than the level (0.10%) obtained by mass screening using physical examination alone in Japan. Moreover, in elderly patients (age over 50 years), the detection rates were higher (0.54%, 1.21%). The number of clinical stage for cases with breast cancer detected by these screening were 5 cases in TIS and 3 in stage I. Thus, all cases were patients with early-stage breast cancer. From these results, mass screening using mammography should be mandatory for elderly women (over 50 years) with asymptomatic breasts.
在德岛县开展了一项使用乳房X线摄影术进行乳腺癌大规模筛查的试验,筛查方式包括在社区进行巡回筛查或在工作场所进行集中筛查。在筛查的第一阶段,使用双视图胶片乳房X线摄影术对乳房进行头尾位和侧斜位成像。此外,还对受试者单独进行了乳房体格检查。在这些试验中,仅通过乳房X线摄影术就发现了8例乳腺癌病例,而通过体格检查未检测到乳腺癌病例。巡回筛查的检出率为0.19%,集中筛查的检出率为0.92%。这远高于日本仅使用体格检查进行大规模筛查所获得的水平(0.10%)。此外,在老年患者(年龄超过50岁)中,检出率更高(0.54%,1.21%)。通过这些筛查检测出的乳腺癌病例的临床分期为Tis期5例,I期3例。因此,所有病例均为早期乳腺癌患者。根据这些结果,对于乳房无症状的老年女性(年龄超过50岁),应强制进行乳房X线摄影术大规模筛查。