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多糖诱导的腹腔内脓肿的结构-功能关系

Structure-function relationships for polysaccharide-induced intra-abdominal abscesses.

作者信息

Tzianabos A O, Onderdonk A B, Smith R S, Kasper D L

机构信息

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, MA.

出版信息

Infect Immun. 1994 Aug;62(8):3590-3. doi: 10.1128/iai.62.8.3590-3593.1994.

DOI:10.1128/iai.62.8.3590-3593.1994
PMID:8039936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC303001/
Abstract

We have previously shown that in an animal model of sepsis positively and negatively charged groups on polysaccharide A of Bacteroides fragilis are essential for the induction of intra-abdominal abscess formation (A. O. Tzianabos, A. B. Onderdonk, B. Rosner, R. L. Cisneros, and D. L. Kasper, Science 262:416-419, 1993). By introducing chemical modifications into the structures of B. fragilis polysaccharide B as well as other abscess-inducing bacterial polysaccharides, we observed the following. (i) The presence of a nonacetylated free amino group on these polysaccharides appears to be required for abscess induction. (ii) No specific type of negatively charged group is essential to abscess induction by these polysaccharides. (iii) The density of free amino groups on these polysaccharides influences this pathobiologic host response.

摘要

我们之前已经表明，在脓毒症动物模型中，脆弱拟杆菌多糖A上的正负电荷基团对于腹腔脓肿形成的诱导至关重要（A. O. 齐亚纳博斯、A. B. 翁德东克、B. 罗斯纳、R. L. 西斯内罗斯和D. L. 卡斯珀，《科学》262:416 - 419，1993年）。通过对脆弱拟杆菌多糖B以及其他诱导脓肿的细菌多糖的结构进行化学修饰，我们观察到以下情况。（i）这些多糖上存在未乙酰化的游离氨基似乎是诱导脓肿所必需的。（ii）对于这些多糖诱导脓肿而言，不存在特定类型的负电荷基团是必不可少的。（iii）这些多糖上游离氨基的密度会影响这种病理生物学宿主反应。

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本文引用的文献

1
Structural features of polysaccharides that induce intra-abdominal abscesses.
Science. 1993 Oct 15;262(5132):416-9. doi: 10.1126/science.8211161.
2
Structure of the complex polysaccharide C-substance from Streptococcus pneumoniae type 1.
Biochemistry. 1980 Sep 30;19(20):4712-9. doi: 10.1021/bi00561a026.
3
Structural studies of the capsular polysaccharide from Streptococcus pneumoniae type 1.
Carbohydr Res. 1980 Jan 1;78(1):111-7. doi: 10.1016/s0008-6215(00)83664-2.
4
Structure of native polysaccharide antigens of type Ia and type Ib group B Streptococcus.
Biochemistry. 1983 Mar 1;22(5):1258-64. doi: 10.1021/bi00274a042.
5
Cellular control of abscess formation: role of T cells in the regulation of abscesses formed in response to Bacteroides fragilis.
J Immunol. 1986 Jul 1;137(1):341-6.
6
Structure and immunochemistry of an oligosaccharide repeating unit of the capsular polysaccharide of type III group B Streptococcus. A revised structure for the type III group B streptococcal polysaccharide antigen.
J Biol Chem. 1987 Jun 15;262(17):8262-7.
7
Evidence for an intercellular covalent reaction essential in antigen-specific T cell activation.
J Immunol. 1989 Sep 1;143(5):1482-9.
8
Erythrocyte rosettes provide an analogue for Schiff base formation in specific T cell activation.
J Immunol. 1990 Jul 15;145(2):463-9.
9
Immunochemical characterization of two surface polysaccharides of Bacteroides fragilis.
Infect Immun. 1991 Jun;59(6):2075-82. doi: 10.1128/iai.59.6.2075-2082.1991.
10
Galactose oxidation in the design of immunogenic vaccines.
Science. 1992 Jun 12;256(5063):1560-3. doi: 10.1126/science.1598588.

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