克罗恩病患者及其一级亲属的肠道通透性
Intestinal permeability in patients with Crohn's disease and their first-degree relatives.
作者信息
Howden C W, Gillanders I, Morris A J, Duncan A, Danesh B, Russell R I
机构信息
Stobhill General Hospital, Glasgow, Scotland, United Kingdom.
出版信息
Am J Gastroenterol. 1994 Aug;89(8):1175-6.
OBJECTIVE
To measure small intestinal permeability in a group of patients with Crohn's disease in clinical remission and their apparently healthy first-degree relatives.
METHODS
Administration of 51Cr-labeled EDTA and subsequent measurement of its excretion in a 24-h urine collection.
RESULTS
Excretion of 51Cr-EDTA was not elevated in either the patients or in first-degree relatives.
CONCLUSION
Intestinal permeability to 51Cr-EDTA is not raised in patients with Crohn's disease in clinical remission or in their healthy first-degree relatives.
目的
测量一组处于临床缓解期的克罗恩病患者及其表面健康的一级亲属的小肠通透性。
方法
给予51Cr标记的乙二胺四乙酸（EDTA），随后收集24小时尿液并测量其排泄量。
结果
患者及其一级亲属中51Cr-EDTA的排泄量均未升高。
结论
处于临床缓解期的克罗恩病患者及其健康的一级亲属对51Cr-EDTA的肠道通透性未升高。
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