斯威特综合征：11例临床病理研究
Sweet's syndrome: clinicopathologic study of eleven cases.
作者信息
Chan H L, Lee Y S, Kuo T T
机构信息
Department of Dermatology, Chang Gung Medical College, Taipei, Taiwan.
出版信息
Int J Dermatol. 1994 Jun;33(6):425-32. doi: 10.1111/j.1365-4362.1994.tb04045.x.
BACKGROUND
The clinicopathologic manifestations of Sweet's syndrome associated with malignancy have been rarely studied in a large series.
METHODS
We describe the clinical features of Sweet's syndrome in 11 patients seen during the past 12 years. Histopathologic findings of these patients are discussed. The clinicopathologic manifestations of 249 cases of Sweet's syndrome reported in the literature were reviewed.
RESULTS
The clinicopathologic manifestations of Sweet's syndrome associated with hematologic disorders (HSS) were more severe and characterized by bullous pyoderma with more pronounced epidermal changes and ulceration, anemia, giant platelets and abnormal platelet counts. Approximately 40% of the Sweet's syndrome reported in the literature were associated with hematologic malignancy, and the other 7% of patients had solid tumors.
CONCLUSIONS
Sweet's syndrome can be classified into three types: (1) association with hematologic disorders (HSS); (2) association with solid tumors (SSS); and (3) idiopathic or associated with various other disorders (ISS).
背景
与恶性肿瘤相关的Sweet综合征的临床病理表现很少在大样本中进行研究。
方法
我们描述了过去12年中诊治的11例Sweet综合征患者的临床特征。讨论了这些患者的组织病理学发现。回顾了文献报道的249例Sweet综合征的临床病理表现。
结果
与血液系统疾病相关的Sweet综合征（HSS）的临床病理表现更为严重，其特征为大疱性脓皮病，伴有更明显的表皮改变和溃疡、贫血、巨大血小板及血小板计数异常。文献报道的Sweet综合征中约40%与血液系统恶性肿瘤相关，另外7%的患者患有实体瘤。
结论
Sweet综合征可分为三种类型：（1）与血液系统疾病相关（HSS）；（2）与实体瘤相关（SSS）；（3）特发性或与其他各种疾病相关（ISS）。
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