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[子宫颈癌盆腔脏器清除术(预后因素)]

[Pelvic exenteration for cancer of the uterine cervix (prognostic factors)].

作者信息

Torres Lobatón A, Bastida Blanco A, Márquez Acosta G, Hernández Aten D, Román Bassaure E, Rojo Herrera G

机构信息

Servicio de Oncología, Hospital General de México, S.S. Méx., D.F.

出版信息

Ginecol Obstet Mex. 1994 Jul;62:189-93.

PMID:8063185
Abstract

The prognostic factors in 104 patients subjected to pelvic exenterations for cervical cancer recurrent after radiation therapy, at The Oncology Service Hospital General de Mexico, S.S., who survived the surgical procedures with a follow-up for three years or more, are presented here. Results were with statistical significance in the next cases: Patients with 35 years old or less, had a better prognosis when compared with the others: 15/22, 68.1%, vs. 36/82, 43.9%, P = 0.03; clinical reports of tumour localized in cervix, 17/22, 77.2%, vs. infiltration of lateral wall of the pelvis: 11/39, 28.2%, P = 0.008. Pyelographic findings of hydronephrosis or renal exclusion: 2/13, 15.3% vs. normal reports: 9/13, 69.2%, P = 0.01. Infiltration of urinary bladder and or rectal wall: 15/41, 36.5% vs. absence of these: 36/63, 57.1%, P = 0.03; tumour involving myometrium with or without ovarian metastases: 2/15, 13.0% vs. absence of these reports: 49/89, 55.5%, P = 0.03 and the absence of lymph metastatic nodes: 40/68, 58.8% vs. the presence of 3 or more positive lymph nodes: 4/15, 26.6%, P = 0.01. In this series we didn't find differences with statistical significance when compared, the modalities of schemes of radiotherapy, the variety of exenterative procedures and the period of time less or more than a year, between the radiotherapy and the surgery.

摘要

本文介绍了墨西哥社会保险总局肿瘤服务医院104例接受盆腔脏器清除术治疗的放疗后复发性宫颈癌患者的预后因素,这些患者术后存活且随访时间达三年或更长时间。在下述情况中结果具有统计学意义:35岁及以下患者与其他患者相比预后更好:15/22(68.1%)对比36/82(43.9%),P = 0.03;肿瘤局限于宫颈的临床报告为17/22(77.2%),对比盆腔侧壁浸润为11/39(28.2%),P = 0.008。肾盂造影显示肾积水或肾排泄异常:2/13(15.3%)对比正常报告:9/13(69.2%),P = 0.01。膀胱和/或直肠壁浸润:15/41(36.5%)对比无这些情况:36/63(57.1%),P = 0.03;肿瘤累及子宫肌层伴或不伴卵巢转移:2/15(13.0%)对比无这些报告:49/89(55.5%),P = 0.03;无淋巴结转移:40/68(58.8%)对比有3个或更多阳性淋巴结:4/15(26.6%),P = 0.01。在本系列研究中,对比放疗方案的方式、各种脏器清除术以及放疗与手术之间间隔时间少于或多于一年的情况,未发现具有统计学意义的差异。

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