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[难治性部分性癫痫的颞叶切除术。4例报告]

[Temporal lobectomy in refractory partial epilepsy. Report of 4 cases].

作者信息

Yáñez A, Morales E, Galdames D, Aguilera L, Fauré E, Ortiz V, Silva C, Villar R, Fenieux C G, Estruch J

机构信息

Servicio Neurología-Neurocirugía, Hospital J J Aguirre, Universidad de Chile, Santiago.

出版信息

Rev Med Chil. 1994 Feb;122(2):186-92.

PMID:8085084
Abstract

Thirty, out of 1200 patients of North Santiago Adult Epilepsy Program, were admitted to J J Aguirre Hospital due to refractory epilepsy. Looking for candidates for functional epilepsy surgery, these patients were evaluated by neurologists, psychiatrists and psychologists and with standard EEG, video monitored EEG, CAT scan, magnetic resonance imaging and SPECT. So far, four patients with temporal partial complex epilepsy have been studied, operated (anterior temporal lobectomy and amygdalo-hippocampectomy) and followed for more than one year. Of these, two are free of seizures, one has sporadic episodes and one has an important reduction. One of these patients had a postoperative amnestic syndrome of 3 to 4 weeks duration. According to these results and those reported in the literature, the rigorous selection of patients that could be benefitted by surgery is emphasized.

摘要

在北圣地亚哥成人癫痫项目的1200名患者中,有30名因难治性癫痫入住J J阿吉雷医院。为寻找功能性癫痫手术的候选者,这些患者接受了神经科医生、精神科医生和心理学家的评估,并进行了标准脑电图、视频监测脑电图、计算机断层扫描、磁共振成像和单光子发射计算机断层扫描。到目前为止,对4例颞叶部分性复杂性癫痫患者进行了研究、手术(前颞叶切除术和杏仁核-海马切除术)并随访了一年多。其中,2例无癫痫发作,1例有散发性发作,1例发作明显减少。这些患者中有1例术后出现了持续3至4周的遗忘综合征。根据这些结果以及文献报道,强调了对可能从手术中获益的患者进行严格筛选。

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