Brook I, de Leyva F
Department of Pediatrics, Georgetown University, School of Medicine, Washington, DC.
Arch Pediatr Adolesc Med. 1994 Feb;148(2):171-3. doi: 10.1001/archpedi.1994.02170020057009.
To compare the cultures of tonsillar surface aerobic and anaerobic bacterial flora taken during the acute phase of infectious mononucleosis with the repeated cultures taken 2 months later.
Fourteen patients with pharyngotonsillitis associated with infectious mononucleosis.
A total of 121 bacterial isolates (ie, 84 anaerobes and 37 facultatives and aerobes) were isolated in the acute stage, and 75 isolates (ie, 42 anaerobes and 33 aerobes) were recovered 2 months later. The reduction in the number of organisms in the second specimen was mostly due to the decrease in the recovery of Prevotella intermedia (13 in the first culture, compared with four in the second) and Fusobacterium nucleatum (12 vs four, respectively).
The study illustrates that the surfaces of tonsils of patients with infectious mononucleosis contain more species of anaerobic organisms during the illness than following it. The potential role of these organisms in the inflammation process warrants further study.
比较传染性单核细胞增多症急性期采集的扁桃体表面需氧和厌氧细菌菌群培养结果与2个月后重复培养的结果。
14例伴有传染性单核细胞增多症的咽扁桃体炎患者。
急性期共分离出121株细菌（即84株厌氧菌和37株兼性菌及需氧菌），2个月后回收75株（即42株厌氧菌和33株需氧菌）。第二个标本中微生物数量的减少主要是由于中间普雷沃菌回收率降低（第一次培养为13株，第二次为4株）和具核梭杆菌回收率降低（分别为12株和4株）。
该研究表明，传染性单核细胞增多症患者患病期间扁桃体表面的厌氧生物种类比患病后更多。这些生物在炎症过程中的潜在作用值得进一步研究。
