Strebel S, Pargger H, Scheidegger D
Departement Anästhesie, Kantonsspital Basel.
Schweiz Med Wochenschr. 1994 Feb 19;124(7):270-3.
The diagnosis of chronic primary and secondary pulmonary hypertension is difficult. Important indications result from physical examination and the patient's history. Non-invasive diagnostic tools are chest X-ray, ECG, blood gas analysis and 2-D-Doppler-echocardiography. If, despite these investigations, no reason for the pulmonary hypertension is found, perfusion scintigraphy of the lungs and a right-heart catheter investigation should be performed. If there is no intracardiac shunting and perfusion scintigraphy of the lungs is normal, repeated pulmonary embolism must be excluded by pulmonary angiography. Only after elimination of this possibility can primary pulmonary hypertension be regarded as the reason for the patient's condition. Pulmonary hypertension is usually more acute in the critically ill patient. Under these circumstances, only direct pressure measurements are of clinical relevance. In the critical care setting, many of the non-invasive methods are either difficult to perform or hard to interpret. Furthermore, many of the typical signs of pulmonary hypertension derived from non-invasive investigations do not appear in acute pulmonary hypertension.
慢性原发性和继发性肺动脉高压的诊断较为困难。重要指征来自体格检查和患者病史。非侵入性诊断工具包括胸部X线、心电图、血气分析和二维多普勒超声心动图。如果尽管进行了这些检查,仍未发现肺动脉高压的病因,则应进行肺部灌注闪烁扫描和右心导管检查。如果没有心内分流且肺部灌注闪烁扫描正常,则必须通过肺血管造影排除复发性肺栓塞。只有排除这种可能性后,才能将原发性肺动脉高压视为患者病情的病因。肺动脉高压在危重症患者中通常更为急性。在这种情况下,只有直接压力测量具有临床意义。在重症监护环境中,许多非侵入性方法要么难以实施,要么难以解读。此外,许多源自非侵入性检查的肺动脉高压典型体征在急性肺动脉高压中并不出现。