Buys H, Pead L, Hallett R, Maskell R
Department of Paediatrics, St Mary's Hospital, Portsmouth.
BMJ. 1994 Mar 12;308(6930):690-2. doi: 10.1136/bmj.308.6930.690.
To assess the ease of use of suprapubic aspiration of urine under ultrasound guidance in babies with fever of uncertain cause and to assess the importance of bacterial counts and pyuria in relation to abnormalities of the urinary tract and the importance of pyuria in the absence of bacteriuria.
Analysis of urine samples obtained by suprapubic aspiration in babies and children from July 1991 to June 1992. The clinical records of the children with bacteriuria and sterile pyuria were examined retrospectively.
Neonatal and paediatric wards of a district general hospital.
508 babies and children who had fever of uncertain cause or were seriously ill.
No difficulties arose in the collection of 545 specimens. Bacteria were isolated from the specimens of 44 children, 24 of whom had abnormalities of the urinary tract. The bacterial count was < 10(8)/l in 18 of the children with bacteriuria, 10 of whom had abnormalities. No white cells were seen in 22 of the 46 bacteriuric specimens; nine of the children with no pyuria had vesicoureteric reflux. 439 of the 499 non-bacteriuric specimens showed no white cells. 60 children had pyuria without bacteriuria.
The use of ultrasound guidance simplifies suprapubic aspiration of urine in babies. Low bacterial counts may be associated with abnormalities of the urinary tract. Laboratory techniques capable of detecting such counts reliably should be used. Pyuria is absent in half of babies and very young children with bacteriuria. It rarely occurs without bacteriuria, and if it does an explanation should be sought.
评估在病因不明发热的婴儿中,超声引导下耻骨上膀胱穿刺取尿的操作便利性,评估细菌计数和脓尿与泌尿道异常的关系,以及无菌性脓尿的重要性。
对1991年7月至1992年6月期间婴儿和儿童耻骨上膀胱穿刺获取的尿样进行分析。对有菌尿和无菌性脓尿患儿的临床记录进行回顾性检查。
一家地区综合医院的新生儿和儿科病房。
508名病因不明发热或病情严重的婴儿和儿童。
545份标本采集过程中未出现困难。从44名儿童的标本中分离出细菌,其中24名有泌尿道异常。18名有菌尿的儿童细菌计数<10⁸/l,其中10名有泌尿道异常。46份有菌尿标本中有22份未见白细胞;9名无脓尿的儿童有膀胱输尿管反流。499份无菌尿标本中有439份未见白细胞。60名儿童有无菌性脓尿。
超声引导简化了婴儿耻骨上膀胱穿刺取尿操作。低细菌计数可能与泌尿道异常有关,应使用能可靠检测此类计数的实验室技术。半数有菌尿的婴儿和幼儿无脓尿。无菌尿时脓尿很少见,若出现应寻找原因。