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非处方可用二十年后洗必泰的使用情况。

Chlorhexidine use after two decades of over-the-counter availability.

作者信息

Albandar J M, Gjermo P, Preus H R

机构信息

Department of Periodontology, Dental Faculty, University of Oslo, Norway.

出版信息

J Periodontol. 1994 Feb;65(2):109-12. doi: 10.1902/jop.1994.65.2.109.

Abstract

Chlorhexidine (CHX) is a compound with plaque-inhibiting effects and available only by prescription in the United States. In Norway, however, CHX has been dispensed over-the-counter for over 20 years, and this study was undertaken to evaluate dentists' perceptions regarding its indications, usefulness, and side effects. A written questionnaire was sent to a sample of 10% of dentists registered in Norway, 78% of whom (354) responded. Additionally, representatives from 2% of all dental practices in Norway were contacted by telephone. Fourteen percent (14%) of the respondents reported that they never recommended CHX to their patients. Among those recommending the compound, 85% used it frequently after surgical periodontal procedures; 74% when treating acute gingivitis; 57% following oral surgery in general; and 35% during non-surgical periodontal therapy. It was used also as an adjunct to other treatment routines. Seventy-three percent (73%) reported frequent use of CHX when treating stomatitis and 54% in herpes simplex infections. As to side effects, 77% of the dentists indicated that staining of teeth, restorations, and the tongue was a major concern to patients; 12% reported inconveniences due to the bitter taste; and 6% reported other disturbances such as dryness of the mouth and development of oral ulcerations. The majority (94%) of the dentists recommended mouth rinsing, whereas 6% recommended a gel form. Only 4% of the dentists recommended rinsing with a patient-diluted 0.1% concentration, whereas 96% recommended the standard 0.2% formulation; 88% recommended using CHX mouthwash twice a day or more often.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

洗必泰(CHX)是一种具有抑制牙菌斑作用的化合物,在美国仅凭处方可得。然而,在挪威,洗必泰非处方销售已有20多年,本研究旨在评估牙医对其适应症、效用及副作用的看法。一份书面问卷被寄给挪威10%注册牙医样本,其中78%(354人)回复。此外,还通过电话联系了挪威所有牙科诊所中2%的代表。14%的受访者表示他们从未向患者推荐过洗必泰。在推荐该化合物的人中,85%在牙周手术后经常使用;74%在治疗急性牙龈炎时使用;57%在一般口腔手术后使用;35%在非手术牙周治疗期间使用。它也被用作其他治疗程序的辅助手段。73%的人报告在治疗口腔炎时经常使用洗必泰,54%在单纯疱疹感染时使用。至于副作用,77%的牙医指出牙齿、修复体和舌头染色是患者主要担忧的问题;12%报告因苦味带来不便;6%报告有其他不适,如口干和口腔溃疡。大多数(94%)牙医推荐漱口,而6%推荐凝胶剂型。只有4%的牙医推荐用患者稀释至0.1%浓度的溶液漱口,而96%推荐标准的0.2%配方;88%推荐每天使用洗必泰漱口水两次或更频繁。(摘要截选至250字)

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