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移植物类型对股动脉以下动脉搭桥移植物通畅率的影响。

The influence of graft type on patency of infrainguinal arterial bypass grafts.

作者信息

Neale M L, Graham J C, Lane R J, Cheung D S, Appleberg M

机构信息

Department of Vascular Surgery, Royal North Shore Hospital, Sydney, Australia.

出版信息

J Am Coll Surg. 1994 Feb;178(2):155-63.

PMID:8173726
Abstract

Between 1985 and 1992, 328 patients underwent 392 infrainguinal reconstructions. Indications for operation were disabling claudication in 126 patients, critical limb ischemia in 246 and uncomplicated popliteal aneurysm in 20. Grafts were to the above knee popliteal artery in 134 patients, below knee popliteal artery in 176 and infrapopliteal ("distal") in 82 patients. Graft types included 160 reversed saphenous vein (RSV), 95 polytetrafluoroethylene (PTFE), 84 nonreversed saphenous vein (NRSV), 41 composite grafts (PTFE plus vein) and 12 others. Results show the five year patency rate for all grafts of 58 percent and limb salvage (for limb ischemia) of 74 percent. Above knee and below knee popliteal grafts (three year patency rates of 72 and 66 percent) performed significantly better than distal grafts (51 percent three year patency rate, p < 0.025). NRSV grafts comprised 63 ex situ ("translocated") and 21 in situ grafts. No significant difference was shown between these (two year patency rates of 62 and 65 percent). There was no significant difference between RSV and NRSV grafts in this series, although RSV tended to show higher patency rates. Composite grafts (below knee, three year patency rate of 45 percent) had significantly lower three year patency rates than below knee RSV (79 percent, p < 0.005). RSV remains the conduit of choice in this unit, with long term patency comparable with other published series. Use of NRSV (translocated and in situ) allows increased use of autogenous vein with the associated higher patency rates compared with prosthetic materials and is the graft of choice if the long saphenous vein is not suitable for use in the standard reversed method. The translocated technique allows more flexibility in the use of nonreversed vein with results comparable with the in situ technique. Composite grafts provide a useful alternative to PTFE alone for infrageniculate grafting when insufficient autogenenous vein is available.

摘要

1985年至1992年间,328例患者接受了392次股下血管重建手术。手术指征为:126例患者有致残性间歇性跛行,246例患者有严重肢体缺血,20例患者有单纯腘动脉瘤。134例患者的移植物用于膝上腘动脉,176例用于膝下腘动脉,82例用于腘下(“远端”)动脉。移植物类型包括160例倒置大隐静脉(RSV)、95例聚四氟乙烯(PTFE)、84例非倒置大隐静脉(NRSV)、41例复合移植物(PTFE加静脉)和12例其他类型。结果显示,所有移植物的五年通畅率为58%,肢体挽救率(针对肢体缺血)为74%。膝上和膝下腘动脉移植物(三年通畅率分别为72%和66%)的表现明显优于远端移植物(三年通畅率为51%,p<0.025)。NRSV移植物包括63例异位(“移位”)和21例原位移植物。两者之间未显示出显著差异(两年通畅率分别为62%和65%)。在本系列中,RSV和NRSV移植物之间没有显著差异,尽管RSV的通畅率往往更高。复合移植物(膝下,三年通畅率为45%)的三年通畅率明显低于膝下RSV(79%,p<0.005)。在本单位,RSV仍然是首选的血管 conduit,其长期通畅率与其他已发表的系列相当。使用NRSV(移位和原位)可以增加自体静脉的使用,与人工材料相比,其通畅率更高,如果大隐静脉不适合用于标准倒置方法,NRSV是首选的移植物。移位技术在使用非倒置静脉时提供了更大的灵活性,其结果与原位技术相当。当自体静脉不足时,复合移植物为膝下移植提供了一种有用的替代单独使用PTFE的方法。

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