Reid W H, Mason M, Toprac M
Texas Department of Mental Health and Mental Retardation, Austin 78711.
Hosp Community Psychiatry. 1994 Mar;45(3):261-4. doi: 10.1176/ps.45.3.261.
The authors' aim was to determine whether clozapine was associated with a decrease in state hospital bed-days for patients with chronic schizophrenia.
Patients were started on clozapine in a state facility and were followed while taking the medication for 1.5 years (N = 172), two years (N = 86), and 2.5 years (N = 53). Patients' number of bed-days before starting clozapine was compared with those during the follow-up period.
Bed-days were reduced by an average of 132 days per year after 1.5 years, 166 days per year after two years, and 201 days per year after 2.5 years (p < .001). During the final 180 days of each follow-up period, only 23 to 30 percent of patients were continuously hospitalized, compared with 56 to 64 percent before clozapine. Forty to 57 percent of patients had no hospital days at all during the last 180 days of follow-up.
Based on hospital costs of $250 per patient per day, this reduction in bed-days could result in gross savings of about $33,000 per patient per year at 1.5 years, $41,500 per patient per year at two years, and $50,250 per patient per year at 2.5 years. Hospital patients are conspicuous targets for clozapine funding, since bed-days represent an easily measured expense. Nevertheless, community treatment should be an even higher priority, since most chronic mentally ill persons are outpatients.
作者旨在确定氯氮平是否与慢性精神分裂症患者在州立医院的住院天数减少有关。
患者在一家州立医疗机构开始服用氯氮平,并在服药1.5年(N = 172)、2年(N = 86)和2.5年(N = 53)期间接受随访。将患者开始服用氯氮平之前的住院天数与随访期间的住院天数进行比较。
1.5年后,住院天数平均每年减少132天;2年后,平均每年减少166天;2.5年后,平均每年减少201天(p <.001)。在每个随访期的最后180天里,只有23%至30%的患者持续住院,而服用氯氮平之前这一比例为56%至64%。在随访的最后180天里,40%至57%的患者根本没有住院天数。
按照每位患者每天250美元的住院费用计算,住院天数的减少可能会带来显著的节省,在1.5年时每位患者每年大约节省33,000美元,2年时每位患者每年节省41,500美元,2.5年时每位患者每年节省50,250美元。住院患者是氯氮平资助的显著目标,因为住院天数是一项易于衡量的费用。然而,社区治疗应该是更高的优先事项,因为大多数慢性精神病患者是门诊患者。