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血红蛋白替代品在贫血的耶和华见证会患者中的应用。

Use of a hemoglobin substitute in the anemic Jehovah's Witness patient.

作者信息

Marelli T R

出版信息

Crit Care Nurse. 1994 Feb;14(1):31-8.

PMID:8194324
Abstract

Fluosol DA is an experimental means of supplementing oxygen delivery in the anemic patient. The drug's ability to improve oxygen transport appears to improve SVO2. Blood transfusion is the first choice for acute anemia secondary to hemorrhage; however, perfluorochemicals offer an alternative for the patient who cannot accept transfusion therapy. This article reports a case of severe anemia in which transfusion was refused because of the patient's religious convictions. Perfluorochemicals represented an effective medical treatment that was compatible with this patient's religious beliefs. Continued research in artificial oxygen transporters may lead to even more effective drugs for the treatment of acute anemia, possibly decreasing the need for blood transfusion for all patients.

摘要

氟碳代血液(Fluosol DA)是一种用于改善贫血患者氧输送的实验方法。该药物改善氧运输的能力似乎能提高混合静脉血氧饱和度(SVO2)。输血是出血继发急性贫血的首选治疗方法;然而,对于不能接受输血治疗的患者,全氟化合物提供了一种替代方案。本文报告了一例严重贫血病例,患者因宗教信仰拒绝输血。全氟化合物是一种与该患者宗教信仰相符的有效治疗方法。对人工氧载体的持续研究可能会带来更有效的治疗急性贫血的药物,有望减少所有患者的输血需求。

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