使用伊维菌素预防螺旋锥蝇幼虫（嗜人瘤蝇蛆）引起的皮肤蝇蛆病。
Prevention of cutaneous myiasis caused by screw worm larvae (Cochliomyia hominivorax) using ivermectin.
作者信息
Anziani O S, Loreficce C
机构信息
Instituto Nacional de Technología Agropecuaria, Estación Experimental Agropecuaria Rafaela, Santa Fe, Argentina.
出版信息
Zentralbl Veterinarmed B. 1993 Jun;40(4):287-90. doi: 10.1111/j.1439-0450.1993.tb00140.x.
During March of 1991 and 1992, four trials were carried out in the central area of Argentina to evaluate the efficacy of ivermectin in the prevention of myiasis caused by Cochliomya hominivorax larvae. In the first trial 24 steers were artificially wounded, in the second and third trial, 36 and 20 bull calves were castrated while in the fourth trial, 30 newborn calves were used. On day 0, half of the animals of each trial was treated with ivermectin (200 micrograms/kg) and the rest remained as untreated controls. None of the treated animals sustained a screw-worm larva infestation, but 3 of 12 (25%), 8 of 18 (44%), 5 of 10 (50%) and 8 of 15 (53%) of the controls developed active myiasis in trials 1 to 4 respectively.
1991年3月至1992年期间，在阿根廷中部地区进行了四项试验，以评估伊维菌素预防人皮蝇幼虫引起的蝇蛆病的效果。在第一项试验中，24头阉牛被人工致伤；在第二项和第三项试验中，分别有36头和20头公牛犊被阉割；在第四项试验中，使用了30头新生牛犊。在第0天，每项试验中一半的动物用伊维菌素（200微克/千克）进行治疗，其余作为未治疗的对照。在试验1至4中，没有一头接受治疗的动物感染螺旋蝇幼虫，但对照动物中分别有12头中的3头（25%）、18头中的8头（44%）、10头中的5头（50%）和15头中的8头（53%）发生了活动性蝇蛆病。
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