Tominaga R, Smith W A, Harasaki H, Golding L A
Department of Biomedical Engineering and Applied Therapeutics, Cleveland Clinic Foundation, Ohio.
Artif Organs. 1993 Sep;17(9):819-21. doi: 10.1111/j.1525-1594.1993.tb00638.x.
Catastrophic pulmonary vasoconstriction after protamine reversal of heparin anticoagulation was observed frequently in goats that underwent centrifugal biventricular bypass pump implant. Care should be taken when protamine is used to reverse heparin anticoagulation in goats.