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[神经源性肌肉肥大]

[Neurogenic muscle hypertrophy].

作者信息

ten Holter J B, van Nieuwstadt M A

机构信息

Afd. Neurologie, Deventer Ziekenhuizen.

出版信息

Ned Tijdschr Geneeskd. 1993 Dec 18;137(51):2655-8.

PMID:8278000
Abstract

Enlargement of the calf usually is associated with venous thrombosis, haemorrhage, focal myositis or a tumour in bone or muscle. Occasionally a calf enlargement is due to isolated muscle hypertrophy as a sign of radicular or peripheral nerve injury. Most neurogenic muscle hypertrophy is confined to the calf muscle, but the phenomenon has also been seen in other muscles. Three patients with S-I radiculopathy leading to ipsilateral neurogenic calf hypertrophy following hernia nuclei pulposi are described, two men of 79 and 78 years old and a woman of 46 years. The symptoms gradually subsided with time and conservative treatment. The pathogenesis of neurogenic muscle hypertrophy possibly involves partial denervation atrophy and compensatory hypertrophy of remaining muscle fibres.

摘要

小腿增大通常与静脉血栓形成、出血、局灶性肌炎或骨骼或肌肉中的肿瘤有关。偶尔,小腿增大是由于孤立性肌肉肥大,这是神经根或周围神经损伤的一种表现。大多数神经源性肌肉肥大局限于小腿肌肉,但这种现象也在其他肌肉中出现过。本文描述了3例因腰椎间盘突出导致同侧神经源性小腿肥大的S-I神经根病患者,其中2名男性,年龄分别为79岁和78岁,1名女性,46岁。随着时间推移和保守治疗,症状逐渐缓解。神经源性肌肉肥大的发病机制可能涉及部分失神经萎缩和剩余肌纤维的代偿性肥大。

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