Auge B, Rodier J F, Pusel J, Janser J C
Laboratoire d'Anatomie Pathologique, Centre Régional de Lutte contre le Cancer, Strasbourg.
Arch Anat Cytol Pathol. 1993;41(3-4):124-8.
We present a new case report of "Insular" thyroid carcinoma. The first series was published, in 1984, by Carcangiu et al. The propensity for local recurrence and early distant metastases explains the poor prognosis of this carcinoma and demands aggressive therapy at the time of diagnosis. This includes radical surgery, radiotherapy with possible chemotherapy. Clinical and pathological arguments suggest that this carcinoma could be an intermediate stage in the process of loss of differentiation of some thyroid neoplasms.