Jeanneau A
SHU, Hôpital Sainte-Anne, Paris.
Encephale. 1993 Sep-Oct;19(5):573-8.
This review of the literature shows that Parkinson's disease can be considered as an indication of sismotherapy. The therapeutic effects of ECT on the extra-pyramidal syndrome are reviewed whether it is associated with a depression or not. The various biological mechanisms of the antiparkinsonian effect of ECT are discussed ie the increase of the permeability of the brain blood barrier, the action on the dopamin metabolism and the dopamin receptors and the action on the opioid receptors and melatonin. The role of maintenance ECT in the treatment of Parkinson's disease is cleared up. In conclusion, it appears that sismotherapy can be considered as an adjuvant therapy in Parkinson's disease especially when there is a resistance to dopatherapy.
这篇文献综述表明，帕金森病可被视为振动疗法的一个适应证。本文回顾了电休克治疗（ECT）对锥体外系综合征的治疗效果，无论其是否与抑郁症相关。讨论了ECT抗帕金森病作用的各种生物学机制，即血脑屏障通透性增加、对多巴胺代谢及多巴胺受体的作用以及对阿片受体和褪黑素的作用。明确了维持性ECT在帕金森病治疗中的作用。总之，似乎振动疗法可被视为帕金森病的辅助治疗方法，尤其是在对多巴胺能治疗有抵抗时。
